A family showing apparent X linked inheritance of both anencephaly and spina bifida.
نویسندگان
چکیده
A family is reported which includes five males, two with spina bifida, two sibs with anencephaly, and one with both high and low spinal lesions. The affected subjects came from four sibships in three generations. The mode of inheritance of these neural tube defects is consistent with X linkage.
منابع مشابه
Brief communication: possible X-linked anencephaly and spina bifida--report of a kindred.
Causal heterogeneity of anencephaly and spina bifida has been demonstrated; in rare families the neural tube defect may be caused by a single gene. We report a family in which four cases of anencephaly or spina bifida may represent X-linked inheritance.
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عنوان ژورنال:
- Journal of medical genetics
دوره 25 4 شماره
صفحات -
تاریخ انتشار 1988